LSD

[Terrance]

I wonder about Muchos and Zoyd's conversations regarding LSD towards the
end 
  of Vineland--re-reading it recently, I wonder if it's Pynchon's way of 
  shining a light once more on the naiveté of the 60s generation that
LSD was 
  the quick way of learning that one wasn't going to die. The view of
LSD in 
  Lot 49 is alot more sinister. I think Pynchon's affections for the
wonders 
  of LSD are evident, but I think he balances that view that it could
also 
  become another vehicle for Control, Irregardless (that word again,
skippy) 
  of whether it's the CIA dispensing or not.

  Rich

I have no idea what Thomas R. Pynchon may think of LSD, but again, can
you provide a single passage from any Pynchon text that supports the
claim that Pynchon or Pynchon's texts evidence an affection for LSD? I
can provide lots of passages from CL, GR, and VL, that have convinced me
that LSD is negative in Pynchon's books.  Moreover, as you note, LSD
represents a peter pan 1960s attitude and naiveté (Pynchon notes this
explicitly in the Slow Learner Introduction)  and a denial of death, an
attempt to escape  Death and thus a denial of life in Pynchon's texts.
LSD is the drug associated with a Nazi doctor in CL.  Consider what
happens to Mucho, he becomes an infantile sloth. In GR, LSD is THEIR
synthetic drug and is explicitly associated with plastic, oil, control,
the sacred rituals of THEM. In VL, it is what Zoyd and Mucho are ga ga
nostalgic for (a big no no in all Pynchon novels) and it is said to
provide them with an x-ray vision, but that vision is a vision of
denial, projection and irresponsibility. 

irregardless is and adverb Non-Standard. 

It's very popular in NYC talk. 

ir(respective) + regardless = irregardless
———————————————————— 
USAGE NOTE: The label Non-Standard does only approximate justice to the
status of irregardless. More precisely, it is a form that many people
mistakenly believe to be a correct usage in formal style but that in
fact has no legitimate antecedents in either standard or nonstandard
varieties. (The word was likely coined from a blend of irrespective and
regardless.) Perhaps this is why critics have sometimes insisted that
there is “no such word” as irregardless, a charge they would not think
of leveling at a bona fide nonstandard word such as ain't, which has an
ancient genealogy.